Modafinil, a wakefulness-promoting agent, is an effective and well-tolerated treatment for excessive daytime sleepiness associated with narcolepsy.
Use this medication as directed by your doctor. Take it with or without food as directed by your doctor. Do not take more than the prescribed dose. Tell your doctor if you have problems with vomiting or diarrhea.
Boosts Your Energy Levels
Taking modafinil tablet australia can help improve your mental alertness, making it easier to concentrate and focus on tasks. It has also been found to boost cognitive performance in sleep-deprived individuals. This makes it a great choice for people who need to stay awake during the day, such as students studying for an exam.
Modafinil, also known as Provigil, is a central nervous system stimulant that helps treat extreme sleepiness caused by conditions such as narcolepsy, obstructive sleep apnea, and shift work sleep disorder. It is taken orally, and a typical starting dose is 200 mg per day. However, this may be increased at your doctor’s discretion.
The medication is absorbed into the bloodstream from the digestive tract and crosses the blood-brain barrier to reach the brain, where it inhibits the reuptake of certain neurotransmitters and promotes wakefulness. The drug is metabolized in the liver by amide hydrolysis and CYP-mediated oxidation, and less than 10% of the administered dose is excreted unchanged.
This medicine is not recommended for use by pregnant women, because it may cause harm to a fetus.
It is also not known whether this medicine passes into breast milk. If you are breastfeeding or plan to breastfeed, speak with your doctor before using this medication. Lastly, this medication may interact with some other drugs. Therefore, tell your doctor and pharmacist about all prescription and over-the-counter medicines, vitamins, and herbal products you are taking.
Helps You Stay Alert
Modalert 200 Australia is part of a class of medications called wakefulness-promoting agents. It is available as an oral tablet and is usually taken once a day in the morning for narcolepsy, sleep shift work disorder, and obstructive sleep apnea/hypopnea syndrome (OSAHS; a condition that causes you to stop breathing or breathe shallowly repeatedly while sleeping and prevents you from getting enough restful sleep).
For OSAHS, it may also be used along with other treatments such as breathing devices. Studies have shown that modafinil increases wakefulness and improves the ability to concentrate. It also decreases drowsiness and makes it easier to get up from bed in the morning. It also reduces the time it takes to fall asleep and the number of times you wake up during the night in shift work disorders. It does not affect mood or cause addiction.
In six large-scale double-blind placebo-controlled studies, patients were given once-daily doses of 200 or 400 mg modafinil or placebo for 4-12 weeks. Efficacy was measured using objective measures such as multiple sleep latency tests and maintenance of wakefulness testing. Across the studies, 8% of patients who took modafinil discontinued because of an adverse event, compared to 3% of those who took a placebo (Roth et al 2007). Modafinil is a racemic compound with two enantiomers that have pharmacokinetic properties that are dissimilar. The wake-promoting activity is thought to be due primarily to the R-enantiomer, which has a longer half-life than the S-enantiomer.
Helps You Concentrate
Modafinil (2-benzhydryl sulfinylacetamide) is a wakefulness-promoting agent first marketed in Europe and now labeled by the United States Food and Drug Administration under the brand name Provigil. It is a psychostimulant, and it acts by enhancing the release of dopamine and norepinephrine in the ventrolateral preoptic nucleus via orexin neuron activation. It also increases dopamine levels in the hypothalamus by inhibiting the reuptake of dopamine and norepinephrine.
It is used to improve wakefulness in individuals with conditions such as narcolepsy, shift work sleep disorder, and obstructive sleep apnea/hypopnea syndrome. It is a safe and effective treatment that is less likely to cause addiction than other stimulants such as methylphenidate (Ritalin) and dextroamphetamine/amphetamine (Adderall). However, long-term or high-dose use can lead to psychological and physical dependence.
Helps You Sleep Better
In narcolepsy patients, modafinil is shown to improve cataplexy (a sudden loss of muscle tone), sleepiness after wakefulness, and the ability to stay awake during scheduled sleeping hours. It also increases daytime alertness and reduces fatigue. Modafinil does not disrupt the normal sleep cycle and can be taken regularly.
Modafinil is a benzyhydrylsulfinylacetamide derivative that acts as a wakefulness-promoting agent. It exerts its effects by blocking a series of neurotransmitters involved in the sleep-promoting and sleep-deprivation states, including noradrenergic, dopaminergic (specifically, the dopamine transporter), GABAergic, glutaminergic, histaminergic, and hypocretin systems.1
It has been shown to increase wakefulness in animal models of narcolepsy and obstructive sleep apnea/hypopnea syndrome, as well as in waking human volunteers.
Modafinil is also effective in patients with shift work disorder and narcolepsy, as well as in individuals who have difficulty sleeping during the daytime. In diary studies, modafinil was shown to decrease the average level of sleepiness during night shift work and the number of episodes of falling asleep at inappropriate times, as compared with placebo. It did not adversely affect the time spent in scheduled sleep and was well tolerated, with headache and nausea being the most common side effects.
Talk to your doctor before taking modafinil, especially if you have depression or other mental illness, or if you take any other drugs, including prescription and over-the-counter medicines, vitamins, and herbal products.